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[Above: guildhouses in the Grote Markt, Antwerp]
How is a city defined?
Legally and juridically a city was a corporate community embodied in its citizens, the adult male heads of households. Economically, by the standards of the 16th and 17th centuries a major city was one with a population of around 100,000 people.
In 1500 there were only four cities of this size: Paris, Venice, Naples and Istanbul. (Antwerp reached this figure briefly in the middle of the 16th century.) By 1600 there were twelve European cities of 100,000 or more: the new arrivals included Lisbon, Seville, London, Rome, and Moscow.